Written by Ben Bunting: BA(Hons), PGCert.
The most common question regarding how does ankylosing spondylite (AS) affect male fertility is whether or not AS interferes with fertility. Ankylosing spondylitis is more common in men, affecting between 0.1.8 percent of the world's population. The most common treatment for AS is TNF-a blockers, and two review papers have shown that these drugs do not affect male fertility. The condition itself can interfere with male fertility, as it can cause varicocele and other abnormalities in sperm.
Men with ankylosing spondylitis
A recent study looked at whether men with ankylosing spondylitis (AS) have lower sperm quality and are less likely to conceive. The researchers also evaluated the sperm's morphology and DNA fragmentation by fluorescence in situ hybridisation. However, the study's findings were not conclusive enough to recommend treatment for AS patients.
A large study of men with AS showed that their ability to conceive is not affected by TNF blockade or TNF inhibitor treatment. The results showed that TNF inhibitors, TNF antagonists, and TNF-a inhibitors had no effect on male fertility. However, it was not possible to determine whether or not TNF blockade or inhibitors of the inflammatory response affected sperm quality in men with AS.
Previously, studies have linked inflammatory arthritis to infertility and erectile dysfunction. However, the impact of inflammatory arthritis on a man's ability to bear children remained unclear. Dutch researchers conducted a systematic review of published data from 1970 to date to determine whether the disease affects male fertility. The authors collected data from eight hospitals in the Netherlands. Overall, the findings show that men with inflammatory arthritis are not more likely to conceive than men without a disease.
Although the overall effect of cyclophosphamide therapy on male fertility was not consistent across the conditions studied, the authors concluded that treatment of patients with spondylitis did not impair male fertility in men with ankylosing spondylitus and rheumazine. Anti-TNF treatment did not appear to affect male fertility, although anti-inflammatory drugs and colchicine were linked with impaired sperm morphology.
Men with rheumatoid arthritis
Inflammatory arthritis is associated with decreased male fertility and erectile dysfunction. Men diagnosed with inflammatory arthritis at the age of reproductive life experience more problems with fertility and childlessness. More studies are needed to better understand how this disease affects male fertility. Ankylosing spondylitis is one of several types of inflammatory arthritis.
A recent review examined the relationship between ARD and male fertility in men. Although ARD has a strong association with reduced male fertility, research has not focused on its implementation in standard clinical practice. The purpose of this article was to review the literature and propose a management algorithm for patients with ARD. We discuss the role of ARD in male fertility, as well as how it affects sexual dysfunction.
To evaluate whether rheumatoid arthritis may affect male fertility, we searched for articles published in English. Our search strategy identified 9735 articles. The titles and abstracts of these articles were checked for duplicates, and 86 were found to meet our eligibility criteria. We noted that all included studies enrolled men with rheumatic disease and had results in at least one outcome category. The most significant category was sexual function, followed by fertility, pregnancy and offspring.
Our study also found that autoimmune disorders are associated with increased risks of male infertility in men with rheumatoisd arthritis. Fortunately, the study's findings have been confirmed by a large number of other studies. And it's time we made our findings available. It's not just about rheumatoid arthritis - we can now better understand how ankylosing spondylitis affects fertility in men with rheumatoid arthritis.
Men with juvenile idiopathic arthritis
Inflammatory arthritis has been associated with male infertility, erectile dysfunction, and hypogonadism. However, it is unknown whether this type of arthritis affects a man's ability to father children. Researchers conducted a multicenter, cross-sectional study of 628 men aged 40 and older who had been diagnosed with inflammatory arthritis. Researchers compared the fertility rates of men diagnosed before the age of thirty to those who were diagnosed afterward.
Women with RA tend to have smaller families, a decreased sperm count, and a lower chance of conceiving. While male fertility is often neglected, there are some studies showing that men with RA may have lower sperm count and impaired gonadal function. And while a low response rate is a result of a self-selected group, there is an association between the disease and infertility.
If your doctor suspects that you have juvenile idiopathic arthritis, he or she will likely recommend testing to confirm the diagnosis. Various laboratory tests are available to help determine the type of arthritis and determine the extent of inflammation and antinuclear antibodies in the affected joints. In addition, tests will help rule out other diseases or injuries that may be causing the symptoms. Treatment goals will generally include physical therapy, diet, and exercise.
Although many factors may influence a man's reproductive health, men with juvenile idiopathic arthritis have no direct link with infertility. During a menstrual cycle, male fertility is not affected by arthritis. In addition, women with juvenile idiopathic arthritis may also be susceptible to pre-ejaculatory hormonal imbalance. However, these men should undergo a full medical assessment to ensure that their conditions don't interfere with their ability to conceive.
Men with psoriatic arthritis
The relationship between men with inflammatory arthritis and male fertility is still largely unknown. Previous research has indicated that men with inflammatory arthritis suffer from impaired male fertility, which is related to problems such as erectile dysfunction and poor sperm quality. The primary outcome of the study was the rate of male fertility. Secondary outcomes included the desired family size and the percentage of men without biological children.
While the study did not identify a specific cause for this low response, it found that men with inflammatory arthritis were more likely to experience infertility than men with less severe forms. Men diagnosed before age 30 had significantly fewer children than those diagnosed between 31 and 40 years of age. Men diagnosed after their peak fertility reached thirty had the lowest rates of infertility, and the highest number of pregnancies occurred in men diagnosed after they had reached 40 years of age.
The two conditions affect approximately 1% to 5% of the adult population. AS and psoriatic arthritis affect male fertility to a minimal extent, but they must be diagnosed by a healthcare provider. In cases where severe symptoms occur, a visit to a health care provider is recommended. A healthcare provider will be able to develop a treatment plan to treat the condition.
The age at which men were diagnosed with IA and a spondylitis-like disease decreased their fertility. Men with IA diagnosed between the ages of thirty and forty-one and those diagnosed after the age of forty-one had significantly lower total fertility. The age at which men were diagnosed with psoriatic arthritis was also a factor, but the difference was not statistically significant.
Men with Behçet disease
There is no clear evidence as to whether men with ankylosing spondylites affect male fertility. In fact, the findings of the systematic review suggest that it does not. In a study, researchers looked at the data collected from men with AS who were treated with infliximab, a TNF-blocking antibody. They analyzed their data, comparing it to data obtained from healthy controls and subjects with the disease. The authors also noted that no differences were found in the levels of inhibin B or seminal analysis among men with AS.
There is some evidence to support this association. Behçet disease (BD) is a multisystemic vasculitis that affects the spine. It is more common in the Far East and the Mediterranean basin. The disease usually affects young adults, ranging from their twenties to their early 30s. Males tend to have more severe cases and more extensive involvement of major organs. Although the association between BD and infertility is unclear, colchicine has been linked to a decrement in fertility in males, though this association has not been verified.
Inflammatory arthritis has been associated with lower male fertility, higher rates of childlessness, and poorer sperm quality, and even increased risk of infertility. In a study by Perez-Garcia and colleagues, the authors included 628 men with ankylosing spondylitis in a cross-sectional, multicenter study. They included men diagnosed with juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, and enteropathic arthritis.
Eight studies have examined the relationship between SLE and male fertility. Two of them assessed the function of the gonadal organs in men with SLE. They also looked at sex hormone levels, semen analysis, and antisperm analysis. These findings led to a comprehensive review of the causes and treatments of male infertility in men with SLE.